Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine pathology in premenopausal women and it is a complex syndrome affecting various systems. Numerous studies have been made about how the PCOS effects on bone metabolism, but currently there is no clear information. Wnt pathway plays important role in the regulation of bone metabolism. The sclerostin(Scl) and Dickkopf-1 (DKK1) inhibit this pathway and they has recently become a therapeutic target of osteo...

Introduction: Congenital adrenal hyperplasia (CAH) due to 11 beta-hydroxylase deficiency (11βOHD) is a rare autosomal recessive genetic disorder. It results defects in adrenal cortisol and aldosterone synthesis. Early diagnosis and initiation of treatment in male patients are essential in order to prevent serious complications. We report a male patient with CAH who developed complications because of late diagnosisCase Report: 44-year-old male patien...